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DNA damage is one of the main factors of cell death caused by ionizing radiation, including single-strand (SSBs) and double-strand breaks (DSBs)

they used a single layer of approx 10.5% (w/v) iodixanol ( = 1.06 g/ml) to purify mouse motoneurons, which remained on top of the density barrier after centrifugation

Apoptosis, primarily mediated by caspase-dependent mechanisms, can be initiated through the extrinsic death receptor or the intrinsic mitochondrial pathway

GARRY, V.F., HOZIER, J., JACOBS, D., WADE, R.L., & GRAY, D.G

One quiets the fire

Furthermore, GSH is critical for detoxification and eliminating electrophilic xenobiotics and participates repair of reversible oxidative damage of protein thiols through S-glutathionylation