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At the end of last year I wrote about 10 medical breakthroughs from 2025 you can read it here: This year Ill start with 5 major clinical trials to watch in 2026

When symptoms are attributed to high B12 intake, they typically include: Skin reactions : Acne-like eruptions or rosacea-type rashes, particularly with hydroxocobalamin injections (listed as rare adverse effects in the product information) Gastrointestinal disturbances : Mild nausea, diarrhoea, or abdominal discomfort Headaches : Occasional reports of headache following B12 injections Anxiety or restlessness : Anecdotal reports, though causation remains unestablished It is crucial to distinguish between symptoms caused by elevated B12 levels and those arising from the underlying conditions that elevate B12

What about quinine, perhaps the best-studied bitter substance in human history

References Arthritis Foundation

Soto ME, Guarner-Lans V, Daz-Daz E, Manzano-Pech L, Palacios-Chavarra A, Valdez-Vzquez RR, et al

What's more concerning is that about 20% of tested supplements contained WADA-banned ingredients that weren't even listed on the labels