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Comment: Many commenters disagreed that removal of the SDOH measures would reduce burden

in my opinion, this is likely random variation given the lack of effect on the primary endpoint and on time-to-worsening CDR (although some are wondering whether a longer trial might be necessary to unveil a true signal)

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Is it possible for prenatal vitamins to have too much folic acid

Nat Commun 6 , 8918 (2015)