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3) Glucagon: energy use + fat mobilisation (the differentiator) This is the third lever

Clinical trials have consistently demonstrated that these medications can help patients achieve significant and sustained weight loss, often 10-15% of body weight

Do not adjust your dose on your own

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or collapse (possible anaphylaxis) Severe abdominal pain (possible pancreatitis) Signs of infection at the injection site (redness, swelling, discharge, or fever) Persistent vomiting or inability to tolerate fluids Chest pain, palpitations, or difficulty breathing Severe dizziness or loss of consciousness For non-urgent concerns, contact your GP or call NHS 111 for advice

Retatrutide can affect kidney function especially if dehydration occurs