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Bioavailability is the most important factor to consider when choosing a supplement

ProTx-II, a selective inhibitor of Nav1.7 sodium channels, blocks action potential propagation in nociceptors

At the same time, ferroptosis is accompanied by excessive ROS production, resulting in depolarization of the mitochondrial membrane potential and opening of the mitochondrial permeability transition pore (MPTP), further leading to cell rupture (Ravingerov et al., 2020)

Purity: Higher absorption means fewer fillers are needed to achieve the desired effect