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Tryptophan-Derived Neurotransmitters Tryptophan serves as the precursor for the synthesis of serotonin (5-hydroxytryptamine, 5-HT, see also Biochemistry of Nerve Transmission) and melatonin ( N -acetyl-5-methoxytryptamine)
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doi: 10.1097/AOG.0000000000003500
There are cellular adaptations involving metabolic or functional alterations that lead to increases in cellular organelles and intracellular accumulations of a variety of endogenous and exogenous substances but allow the cell and animal to survive and often live normally