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Our integrated uniform manifold approximation and projection (UMAP) encompassing fetal to pediatric/adult small intestinal epithelium scRNA-seq data identified differentially positioned epithelial cells depending on sample age (1 st trimester, 2 nd trimester, and pediatric/adult), inferring age-dependent epithelial characteristics (Fig

However, it remains unclear whether DPP4 cleavage regulates the biological activity of HMGB1 in vivo

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(b) poor safety

Funding Open access funding provided by the Department of Medicine, University of Perugia