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Recent analyses have raised questions about psychiatric side effects, particularly mood changes and anxiety. Patients with asthma may be at increased risk of respiratory complications, and nutrient deficiencies can occur with long-term therapy. Monitoring mental health and nutritional status should be part of any GLP-1 program

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The most frequently reported side effects were mild to moderate nausea and diarrhea

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Retatrutide is an investigational triple-agonist peptide designed to activate: GLP-1 (Glucagon-Like Peptide-1) receptors GIP (Glucose-Dependent Insulinotropic Polypeptide) receptors Glucagon receptors By targeting all three pathways, retatrutide addresses appetite regulation, insulin resistance, energy expenditure, and fat metabolism together rather than focusing on appetite suppression alone

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It is important to note that these medications are approved to be used in conjunction with lifestyle modifications

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