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GLP-1 is an endocrine hormone secreted by enteroendocrine L-cells located in the distal jejunum, ileum and colon that express the glucagon gene and produce proglucagon (Lee et al., 1990)

Non-response doesn't mean failureit signals that your body's metabolic pathways may require a different therapeutic approach

Working with a registered nutritionist or dietitian can help figure out your individual protein needs, and provide further support with your overall nutrition

Furthermore, exenatide has been demonstrated to mitigate mitochondrial oxidative stress, reduce Ca 2 overload, inhibit fission, and close the mitochondrial permeability transition pore (mPTP), collectively preventing cardiomyocyte apoptosis by inhibiting the release of proapoptotic proteins such as cytochrome c and caspase-3 [94]