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Discussion Potential Protective Mechanisms of SGLT2 Inhibition Associated with Weight Loss Intensive lifestyle measures may result in clinically significant weight reduction (at least 5%) that can be maintained in the long term [40], and a minimum 3% reduction in weight is advantageous for metabolic control [41]

Ozempic is injected once a week subcutaneously (under the skin), while metformin is an oral medication you take by mouth, usually once or twice daily

"Athletes tend to have a higher muscle mass than the general population which can put their BMI in the overweight or obese category," Gregg explains

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