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Alexander Weber, an orthopedic surgeon and chief of sports medicine at the University of Southern California who has published a review of the evidence

Notably, negative correlations were found between performance on the ROCF test and white matter volume in both the left and right genu of the corpus callosum, extending to the cingulum bundle, as well as glucose metabolism in the right dorsal anterior cingulate gyrus of individuals diagnosed with visuoconstructive deficit (VCD)