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Patients with IIH have increased leptin levels in the CSF, whereas other patients with obesity (but without IIH) have decreased leptin levels in the CSF [9]

Back Holst, JJ (26 April 2019) 'From the Incretin Concept and the discovery of GLP-1 to today's diabetes therapy', Frontiers in Endocrinology , 10

Within minutes of starting to eat, however, cells in your gut also rev into action and start secreting two peptide hormones--glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)

The medicines could provide an excellent off-ramp to weekly injections, Dushay said

The same applies to semaglutide

PubMed , Lffler, Dennis, et al