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Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation

Esta observacin, aunque alentadora, debe interpretarse con prudencia: la ausencia de evidencia de efectos secundarios no es una prueba de ausencia

In Asn synthetase-mediated enzymatic reactions, Gln provides an amino group, which combines with -aspartate-AMP to form asparagine (Asn) and AMP

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Ip added the study has paved the way for a larger phase three randomised trial to confirm the drug's neuroprotective potential

Recovery: 2 to 3 weeks