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Following approval, enjoy comprehensive care coordination, including pharmacy support services and ongoing consultation with your care team to fine-tune your treatment plan

Because there were potential reproductive abnormalities observed in preclinical toxicity studies in Sprague Dawley rats and cynomolgus monkeys (see Supplementary Results for complete details of these preclinical studies), out of an abundance of caution, we restricted female subjects to postmenopausal women of nonchildbearing potential

Pataer A, Fanale MA, Roth JA, Swisher SG , Hunt KK

The idea of combining them is, frankly, compelling

The strength and stiffness of these fibrils are influenced by the degree of cross-linking between collagen molecules, which is regulated by enzymes such as lysyl oxidase

Histological analyses Following dissection, epididymal white adipose tissue (eWAT), inguinal white adipose tissue (iWAT) and liver were promptly fixed in a 10% formalin-buffered solution (Sigma-Aldrich)