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Nov 2006;319(2):847-856

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In contrast, curcumin has demonstrated coordinated inhibition of DNMTs (DNMT1, DNMT3A, DNMT3B), suppression of histone deacetylases (HDAC1, HDAC3), and modulation of non-coding RNAs and m 6 A RNA methylation within the same cellular context

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The potential benefits of vitamin D include enhancing endothelial function and promoting the production of endothelial nitric oxide synthase (eNOS), as well as reducing inflammation-induced endothelial dysfunction [144]