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Milham, S

Free radicals damage your cells, DNA, and proteins, accelerating the aging process and increasing your risk of disease

Preclinical models have shown that senolytic compounds like navitoclax or flavonoid-based combinations (e.g., fisetin) can reduce cartilage degradation and synovial inflammation by clearing senescent cells (Fernandez-Moreno et al., 2025

doi: 10.1038/s41380-023-02071-6 103

Still, for people with copper-metabolism disorders or with repeated/systemic exposure, copper burden is a real theoretical concern that has not been studied in humans

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