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The nuclear translocation of activated AKT induced the phosphorylation of FoxO proteins which evoked the 14-3-3-mediated export of FoxO proteins from the nuclei

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The GSH depletion which was observed in the present study [Table/Fig-1] can be caused by acetaldehyde accumulation [32], and increased utilization by the glutathione-S-transferases as well as GGT, the enzymes which are involved in the detoxification of xenobiotics

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