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The medications resist being degraded by DPP-4, which is the enzyme that breaks down naturally produced GLP-1 within a few minutes
Studies have shown significant effects on body weight, glucose metabolism, and overall metabolic function
native GLP-1 significantly improved LV function at peak stress and at 30 min into recovery, predominantly in ischemic segments [75]
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In a randomized controlled trial (gold standard type of study) of 166 patients, a GLP-1 analog (ROSE-010) led to significantly greater pain relief compared to placebo 5