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Prioritizing Patient Safety Every Step of the Way From initial medical screening and lab testing to ongoing provider communications, every element of the Success by Sesame program is designed to maximize safety

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Adipose tissue in obesity-related inflammation and insulin resistance: cells, cytokines, and chemokines

Weight-based dosing challenges, accelerated drug clearance, and adipose-driven immune activation all conspire to undermine therapeutic response

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Common Side Effects Mild nausea (most common, usually improves within a few weeks) Diarrhea or constipation due to slowed digestion Bloating or fullness after meals Mild headaches or fatigue Less Common But Serious Side Effects Pancreatitis (rare) Watch for persistent, severe abdominal pain. Hypoglycemia (rare in non-diabetics) Can occur when combined with insulin therapy. Allergic reactions (very rare) Monitor for rash, swelling, or difficulty breathing