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both require medical evaluation, contraindication screening, and ongoing monitoring by a qualified healthcare provider

However, they are not without potential side effects

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This proliferative effect was accompanied by upregulation of IGF-1 and VEGF messenger RNA expression (meaning the cells were making more of both growth-promoting proteins) and downregulation of TGF-beta1 messenger RNA expression (meaning the cells were producing less of the growth-inhibiting signal that triggers premature catagen)