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[1] [2] As of 20242025, retatrutide remains under clinical investigation and has not been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the United Kingdom, nor by the European Medicines Agency (EMA) or the US Food and Drug Administration (FDA) for routine clinical use

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Tirzepatide, also known as MOUNJARO or ZEPBOUND, is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist