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Currently, the targeting objects of these multifunctional drug delivery nanoplatforms are mainly focused on the inflammatory microenvironment of arthritis (such as infiltrating M1-type macrophages and TNF-) and FLS, aiming to eliminate the adverse effects of these factors [52,53,54]

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Dependent on the type of pigmented lesion, focal pigmentations include amalgam tattoos, melanotic macules, and melanocytic nevi

To alleviate nausea and vomiting, it is advised to stay hydrated and eat a mild diet until the symptoms improve