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Additionally, compared with wild-type cells, PIK3CA mutant colorectal cancer (CRC) cells exhibit elevated anaplerotic -KG production and ATP generation from glutamine
TCA cycle genes are enriched in the Theileria essentialome , related to Figure 4
blood pressure, heart rate)
Characterized by excessive fat accumulation in the liver, NAFLD can progress to more severe conditions, including nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and even liver cancer
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