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Closely related astrocytic end-feet processes are responsible for regulating endothelial cell differentiation and inducing and maintain BBB properties
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This indicates that felinine production downregulates cholesterol biosynthesis, as the in vivo synthesis of cholesterol is affected by cholesterol intake, resulting that Tsushima leopard cats may use more isopentenyl diphosphate for the cholesterol biosynthesis rather than felinine production in winter season as compared to Iriomote cats
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DSIP has also been implicated in the regulation of several endocrine pathways
10.1016/j.biopha.2006.07.015 34 GamageA
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