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389 The use of methadone, naltrexone, or buprenorphine is an effective means of reducing illicit drug use and its complications

A key advantage of the gradual dose-increase approach is its gentle introduction of the medication to your body

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After repeated administration, rats in the short-access paradigm exhibited lower daily and cumulative METH intake than saline controls, with this effect becoming apparent on the second day of treatment and continuing throughout the study, while LIR did not affect METH-taking behavior in the extended-access paradigm