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This prolonged exposure amplifies the drug's irritating effects on the gastric mucosa, and the combination may trigger nausea, reflux, or discomfort that compounds GLP-1-related digestive adjustments

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doi:10.1093/hmg/ddl252

For patients with heart disease, understanding genetic predispositions becomes even more important because the right medication choice reduces the risk of adverse events while maximizing cardioprotective benefits

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Semaglutide is typically administered weekly, while hormone therapy may involve treatments every few months