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TB4 is found extracellularly in blood plasma and wound fluid, possibly regulating cell motility and angiogenesis by interacting with cell surface ATP synthase enzymes [26]

While we recognize that there are certain unknowns regarding the cost of technologies like the Optellum LCP service, we believe it would be unlikely for the cost to be 90 percent less than the initial estimated costs based on our ( review of the information provided in the New Technology APC application

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