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Further development continued in the HERMIONE Phase II trial, although clinical success was constrained by tumor heterogeneity and variability in HER2 expression

Industry analysts estimate that small-molecule production costs could be 10-100 times lower than peptide biologics

A Phase 2 substudy found that retatrutide produced up to 26.1% reduction in total body fat mass while limiting lean mass loss to 6.5kg

Uses & Potential Benefits Here are the commonly cited uses and what the research actually shows