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Mechanism of Action: Tirzepatide vs Exendin-4-Based GLP-1 Agonists Clinical Efficacy and Safety Profile of Mounjaro Prescribing Mounjaro in the UK: NICE Guidance and Patient Selection Scientific References Frequently Asked Questions Understanding Exendin-4 and Its Role in Diabetes Treatment Exendin-4 is a naturally occurring peptide originally isolated from the saliva of the Gila monster lizard ( Heloderma suspectum )