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Study limitations Oral NAC is associated with gastrointestinal discomfort, nausea, and diarrhea, but these symptoms are generally mild and occur at similar rates in placebo groups, indicating that NAC is well-tolerated and safe for chronic use [108]

[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., Heninger G.R., Bowers M.B., Jr., Charney D.S

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