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Obesity (Silver Spring) 2024;32:16131631

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Unlike tirzepatide, retatrutide is not yet FDA-approved or commercially available for prescription use

Other trials of GLP-1 RAs have also not yet provided a clear answer

While semaglutide activates GLP-1 receptors, and tirzepatide activates both GIP and GLP-1 receptors, retatrutide also activates a third glucagon

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