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Bloating and abdominal discomfort are common during the first few weeks and typically improve as the body adjusts to delayed gastric emptying

But for many people, the first few weeks come with something unexpected a noticeable dip in energy

Efficacy and safety at 1mg have not been established in published trial data

Given Lilly's aggressive patent protection strategy (as seen with tirzepatide), affordable retatrutide options through compounding may be limited initially

Strength training twice a week is a solid baseline

The amount of GLP-1 that is perfect for someone (even at a microdosing level) could be too little or too much for someone else