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The article describes limited safety data in advanced renal disease, so it calls for careful evaluation, closer monitoring, and nephrology input when estimated GFR is very low

Glycine regulates protein turnover by activating protein kinase B/mammalian target of rapamycin and by inhibiting MuRF1 and atrogin-1 gene expression in C2C12 myoblasts

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The relative abundance of di- and triacylglycerol lipids increased ~2-fold in ESA and ESA + fer-1-treated cells compared to untreated controls, consistent with ESA being incorporated into storage lipids (Fig

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