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She has struggled with her weight since she was little, but GLP-1 drugs have recently helped her

This study used targeted genetic models to pinpoint the mechanisms of Akkermansia in mice genetically engineered to lack intestinal FFAR4 which is known to regulate metabolism, lipogenesis, and gluconeogenesis

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The approach works best for two populations: patients tapering to maintenance after reaching goal weight, and patients whose GI sensitivity prevents tolerating the standard 0.25 mg starting dose

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