& Kiens, B
Thats why clinical outcomes with GLP-1 therapy dramatically outperform diet and exercise alone not because the medication does all the work, but because it removes the biological barriers that made sustainable weight loss nearly impossible
Targeting Pre-Diabetes and Insulin Resistance Pre-diabetes is a condition where blood sugar levels are higher than normal but not high enough yet for a diagnosis of type 2 diabetes
Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food. Diabetes, vol
Eli Lilly subsequently attempted to patent this as their discovery but it was rejected in court due to the prior publication by Bloom's group (Bloom email)
Patients who communicate early about side effects are often easier to support than patients who wait until nausea, constipation, fatigue, or poor intake has already disrupted treatment
