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250,251 At the same time, ethanol can directly affect the activities of MAT, BHMT, and other enzymes, interfere with Met metabolism, inhibit GSH formation, and weaken the antioxidant capacity of cells

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Methods Patients and study design The study protocol was conducted in accordance with the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University of Medicine