Side effect comparison All three compounds share a similar gastrointestinal side effect profile, which is expected given that all three activate the GLP-1 receptor
This extensive evaluation did not find a causal relationship between a therapy with incretin-based therapies and pancreatic safety
Effects of Glucagon-Like Peptide-1 Receptor Agonists Liraglutide and Semaglutide on Cardiovascular and Renal Outcomes Across Body Mass Index Categories in Type 2 Diabetes: Results of the LEADER and SUSTAIN 6 Trials
If side effects are intolerable, options include staying at a lower dose longer before increasing, using anti-nausea medications more aggressively, or discontinuing and considering alternative medications
PlexusDx maps 14 metabolic and peptide-signaling pathways across 49 peptides, providing 150+ genetic insights that reveal your individual risk profile for GLP-1 side effects
Brand-Name GLP-1 Medications Online FDA-approved GLP-1 medications available online include: Wegovy (semaglutide for obesity) Ozempic (semaglutide for type 2 diabetes) Zepbound (tirzepatide for weight management) Mounjaro (tirzepatide for diabetes) Saxenda (liraglutide for weight loss) Rybelsus (oral semaglutide for weight management) Foundayo (orforglipron for weight loss) These are typically dispensed through a licensed pharmacy in prefilled injection pens or oral tablets in some cases