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The FDA requires the packaging of most anti-seizure medications, including Topamax, to contain a warning about the possibility of suicidal thoughts
10.1016/j.tips.2017.02.005 6 AngelovaP
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Accessed January 4, 2024.
In HFD-fed Atg7 cKO mice and Parkin KO mouse models, some investigators found that deletion of Atg7 and Parkin inhibited mitophagy increased lipid accumulation, and exacerbated diastolic dysfunction, whereas injection of Tat-Beclin1 (TB1) increased mitophagy and attenuated cardiac dysfunction [174]
Though currently only FDA-approved for type 2 diabetes and obesity, the FDA does not restrict people with type 1 from using these drugs
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