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There might be weeks where the scale doesn't move as much, or you feel a bit tired

Chronic stress can make it harder to maintain a healthy weight, no matter how much you exercise or watch your diet

The introduction of an oral option is widely seen as a potential inflection point for obesity treatment, with experts noting it could broaden access and support wider uptake as the category continues to expand

Those exposed to environmental stressors affecting skin health

Semaglutide fatigue often: Appears during weeks 14 Returns briefly after dose increases Improves once nutrition and hydration are balanced Persistent or severe fatigue is less common and usually means something needs adjusting

J Exp Bot 61(1):143156