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Common step therapy requirements include trying metformin first (if type 2 diabetes is present), trialing a GLP-1 single-agonist like semaglutide (Ozempic or Wegovy) before moving to the dual-agonist tirzepatide, and documenting inadequate response or intolerable side effects on the prior medication

On a global level, the virus is two to three times more common in men than in women, and particularly more frequent in men who have sex with men when compared to heterosexual men

All combination data comes from anecdotal clinical observations or theoretical synergy based on separate mechanisms

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This dual action helps maintain better control over blood glucose levels, particularly in people with Type 2 diabetes

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