Every time you use a nasal spray, there's a small but real chance of introducing bacteria from your nasal passages or the surrounding air back into the bottle
SIBO Root Cause Category #2: Structural Issues Even with a fully functional MMC, bacteria and archaea can still overgrow if they get stuck in the small intestine or if they migrate backward from the large intestine
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Another possibly beneficial and important effect of DSIP is its importance in withdrawal from opioids, when, together with exogenously administered morphine, it was able to modulate opioid peptidergic systems, and in chronic pain, where the results of the study stated a significant reduction in pain attacks in patients with chronic pain and depressive states