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doi: 10.1073/pnas.0704329104 318 FarahCMichelLYMBalligandJL

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Calibrate physicians have more flexibility to customize treatment plans based on individual metabolic profiles and comorbid conditions

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The two incretin peptides that enable this effect are the glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide 1 (GLP-1), which have cognate receptors (GIPR and GLP-1R) on islet -cells as well as in other tissues

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