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SR-A1 and MARCO (SR-A6) are key receptors in this process

No significant elevations in cortisol or other adverse endocrine effects reported in clinical studies [2]

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Furthermore, ROS-induced activation of MAPK cascade in response to stimuli is also known to regulate ROS production through feedback mechanisms

Brain tissues and arterial blood were harvested at 1, 3, 7 and 28 days after ICH for immunohistochemistry analysis of Iba-1, DARPP-32 and HO-1, morphological analysis by HE staining and inflammatory factor release tests by ELISA