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Because of the shorter half-life, missed doses do not produce significant accumulation issues, but they also do not produce as sustained a clinical signal as a more stable peptide

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We hypothesized that leptin reduction is a prerequisite for these compounds to fully unravel their weight loss potential

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in Wuhan, China), and the supernatant was collected after centrifugation at 4 C, 16,000 g for 10 min

doi: 10.1016/S2213-8587(20)30038-3 105 MendisBSimpsonEMacDonaldIMansellP