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"These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones," says Jena Shaw Tronieri, Senior Research Investigator at Penn's Center for Weight and Eating Disorders and a co-author of the study

Aydin S, Islamoglu SC, Oz A Children (Basel, Switzerland) 2025

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4 HDAC inhibitors in oncology Histone deacetylase inhibitors demonstrate significant potential in the treatment of various hematologic malignancies and solid tumors

"Retatrutide, a GIP, GLP-1, and glucagon receptor agonist for obesity: A phase 2 trial." New England Journal of Medicine , 389(6), 514-526