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TG2-mediated modification of the GST tag caused aggregate formation but did not affect its glutathione binding affinity

When to actually restart a cycle

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Side effects are rare and generally mild, making it accessible even for individuals with sensitive systems

15 ROS include radical compounds, such as superoxide, hydroxyl radicals, and lipid hydroperoxides, and reactive nonradical compounds, such as singlet oxygen, hydrogen peroxide (H 2 O 2 ), hypochlorous acid, chloramines, and ozone

Oxidative stress has been highlighted as an important contributor to both apoptosis [201] and eryptosis [202]