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Journal reference: Corrao S, Pollicino C, Maggio D, Torres A and Argano C (2024) Tirzepatide against obesity and insulin-resistance: pathophysiological aspects and clinical evidence

doi: 10.1097/MED.0b013e328340ff93

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This may be due to reduced neutrophil infiltration, matrix metalloproteinase 9 (MMP9) levels, and cysteine availability, which impaired the synthesis of collagen, secreted protein acidic and rich in cysteine (SPARC), and cysteinyl leukotrienes, all of which contribute to fibrotic remodeling [126]

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