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5 Safety, clinical tolerability, and periconception management strategies From the perspective of actionable clinical management, this section categorizes three core challenges associated with the use of GLP-1RAs in women of reproductive age with PCOS: (i) discontinuity in adherence driven by gastrointestinal adverse effects

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Some theories include: A response to blood vessel widening Changes in the nervous system The body adjusting to lower blood pressure The good news is that this small increase in heart rate doesnt seem to cause problems