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M.O'SullivanJ
[4] The relatively rapid escalation used in the Phase 2 studies likely contributed to the high adverse-event rates and to the notable discontinuation seen in the obesity trial
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Notably, some of the present studies found that appropriate aerobic exercise and reasonable dietary intervention could induce lipophagy [8] in the liver through multiple pathways, making the combination strongly be recommended for improving MAFLD [9]
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