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20% of body weight) are more likely to notice hair loss with GLP-1 RA usage.[ref] Studies note that this also occurs with other forms of weight loss, like bariatric surgery, and could be tied to reduced intake of nutrients such as protein, iron, biotin, or zinc

While semaglutide targets a single GLP-1 receptor and tirzepatide activates two receptors , retatrutide simultaneously engages three distinct receptor pathways

Theoretically, increasing GLP-1 before a meal may decrease appetite and the amount eaten

Typical symptoms: Constipation (most frequent) Bloating after eating small amounts Occasional loose stools If youre considering an alternative option, read this complete guide: Liraglutide weight loss complete beginner guide

This 9mg option may become the most commonly prescribed dose when retatrutide receives FDA approval, which analysts expect could happen as early as 2027

Implications for CPG brands: Growing GLP-1 use is reshaping grocery spending, as users typically shift toward items low in sugar but high in protein , fiber, and healthy fats, and away from products high in sugar and carbohydrates